abstract：BACKGROUND AND PURPOSE:Carotid artery disease (CAD) is able to critically impair cerebral autoregulation which increases the risk for stroke. As therapeutic strategy largely depends on the degree of CAD, we investigated whether this gradation is also related to significant changes in autoregulatory capacity. We applied...

journal_title：Acta neurologica Scandinavica

authors： Haubrich C,Klemm A,Diehl RR,Möller-Hartmann W,Klötzsch C

更新日期：2004-03-01 00:00:00

abstract：:In a previous study we found that nine of 47 siblings to multiple sclerosis (MS) patients with a normal neurological examination carry an intrathecal oligoclonal immunopathy with limited specificity, a condition we termed MS immunopathic trait. The purpose of this study is to further characterize the MS immunopathic t...

journal_title：Acta neurologica Scandinavica

authors： Haghighi S,Andersen O,Odén A,Rosengren L

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVE:To investigate dopamine reuptake sites (dopamine transporter) in the caudate nucleus and putamen in narcolepsy. PATIENTS AND METHODS:Ten patients with narcolepsy and 15 controls were studied with positron emission tomography. A cocaine analogue [11C]-CFT was used as a radioligand. RESULTS:The uptake of[11C]...

journal_title：Acta neurologica Scandinavica

authors： Rinne JO,Hublin C,Någren K,Helenius H,Partinen M

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVES:Studies demonstrating reduced quality of life and psychological well-being in multiple sclerosis (MS) have typically investigated patients within more advanced stages of disease. The aim of the present paper was to evaluate the emotional burden and quality of life of recently diagnosed MS patients and their ...

journal_title：Acta neurologica Scandinavica

authors： Janssens AC,van Doorn PA,de Boer JB,van der Meché FG,Passchier J,Hintzen RQ

更新日期：2003-12-01 00:00:00

abstract：OBJECTIVE:In a previous study, we found that nine of the 47 siblings to multiple sclerosis (MS) patients with a normal neurologic examination carry an intrathecal oligoclonal immunopathy with limited specificity, a condition we termed MS immunopathic trait. Here we searched for neurological dysfunction with increased s...

journal_title：Acta neurologica Scandinavica

authors： Haghighi S,Frisén L,Odén A,Andersen O

更新日期：2003-11-01 00:00:00

abstract：OBJECTIVES:The common prion protein gene (PRNP) codon 129 polymorphism modifies the susceptibility to and the phenotype of prion diseases. However, no truly representative normal population-based data, or data stratified according to age or gender are available on the distribution of this polymorphism. MATERIAL AND ME...

journal_title：Acta neurologica Scandinavica

authors： Nurmi MH,Bishop M,Strain L,Brett F,McGuigan C,Hutchison M,Farrell M,Tilvis R,Erkkilä S,Simell O,Knight R,Haltia M

更新日期：2003-11-01 00:00:00

abstract：OBJECTIVE:To clarify the optimum trace count for jitter calculation. MATERIALS AND METHODS:Single-fiber electromyography was performed during voluntary contraction (VC-SFEMG) of extensor digitorum muscle in six healthy and five myasthenic subjects. Twenty single-fiber action potential (SFAP) pairs were recorded from e...

journal_title：Acta neurologica Scandinavica

authors： Baslo MB,Yalinay P,Yildiz N,Ertaş M

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the clinical course of patients with myasthenia gravis (MG) up to 3 months after double filtration plasmapheresis (DFP). MATERIAL AND METHODS:We recorded the MG score and measured the level of acetylcholine receptor antibody (AchRAb) at baseline and day 1 (D1), week 1 (W1), 1 month (M1), 2 (M2) a...

journal_title：Acta neurologica Scandinavica

authors： Yeh JH,Chen WH,Chiu HC

更新日期：2003-09-01 00:00:00

abstract：OBJECTIVES:Oxidative stress and glutamate-mediated excitotoxicity may play an important role in the etiopathogenesis of amyotrophic lateral sclerosis (ALS). Prostaglandin E2 (PGE2) activity can be associated with motor neuron death by inducing free radical formation and glutamate release from astrocytes. The aim of thi...

journal_title：Acta neurologica Scandinavica

authors： Iłzecka J

更新日期：2003-08-01 00:00:00

abstract：OBJECTIVES:To investigate eventual differences between women and men with Parkinson's disease (PD) before and after surgery, with respect to clinical status, disability and health-related quality of life (HRQoL). MATERIAL AND METHODS:Twenty-four men and 14 women with PD received a total of 46 surgical procedures (pall...

journal_title：Acta neurologica Scandinavica

authors： Hariz GM,Lindberg M,Hariz MI,Bergenheim AT

更新日期：2003-07-01 00:00:00

abstract：OBJECTIVES:The aim of this pilot study was to evaluate a psychological therapy program used in the treatment of multiple sclerosis (MS) and including cognitive/behavioral strategies, relaxation training and physical exercise. MATERIAL AND METHODS:The participants were 29 patients with MS recruited from an outpatient u...

journal_title：Acta neurologica Scandinavica

authors： Tesar N,Baumhackl U,Kopp M,Günther V

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVES:To examine the mechanisms of alternative strategies developed by stroke patients to compensate their motor impairment and their role in recovery. MATERIAL AND METHODS:The three-dimensional kinematics of the upper limb were quantified during unconstrained reaching movements in seven healthy individuals and i...

journal_title：Acta neurologica Scandinavica

authors： Roby-Brami A,Feydy A,Combeaud M,Biryukova EV,Bussel B,Levin MF

更新日期：2003-05-01 00:00:00

abstract：OBJECTIVES:Focal brain ischemia induced in rodents by occlusion of the middle cerebral artery (MCA) is a widely used paradigm of human brain infarct. The objective of this study is to compare the effectiveness and reproducibility of MCA filament occlusion model in rats and mice. MATERIALS AND METHODS:A total of 140 ro...

journal_title：Acta neurologica Scandinavica

authors： Ardehali MR,Rondouin G

更新日期：2003-04-01 00:00:00

abstract：:Muscle cramps are involuntary, painful, sudden contractions of the skeletal muscles. They are present in normal subjects under certain conditions (during a strong voluntary contraction, sleep, sports, pregnancy) and in several pathologies such as myopathies, neuropathies, motoneuron diseases, metabolic disorders, hydr...

journal_title：Acta neurologica Scandinavica

authors： Parisi L,Pierelli F,Amabile G,Valente G,Calandriello E,Fattapposta F,Rossi P,Serrao M

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVE:The coincidence of coagulatopathy and chronic subdural haematoma (CSH) requires correction of coagulation to facilitate surgery. We investigated the correlation between coagulopathy and outcome in CSH patients. MATERIAL AND METHODS:We analysed past medical history, surgical treatment and coagulation paramete...

journal_title：Acta neurologica Scandinavica

authors： König SA,Schick U,Döhnert J,Goldammer A,Vitzthum HE

更新日期：2003-02-01 00:00:00

abstract：:While chewing and grinding movements have been observed in amphetamine addicts, recognition and management of this problem have rarely been highlighted. Botulinum toxin (BTX) has previously been demonstrated to be effective for bruxism associated with movement disorders, such as cranial-cervical dystonia. However, the...

journal_title：Acta neurologica Scandinavica

authors： See SJ,Tan EK

更新日期：2003-02-01 00:00:00

abstract：OBJECTIVES:To clarify the clinical variability, including central nervous system (CNS) involvement, in X-linked Charcot-Marie-Tooth disease (CMTX) patients. MATERIAL AND METHODS:We clinically, pathologically and genetically studied six CMTX patients with distinct symptoms and four different GJB1 mutations. RESULTS:On...

journal_title：Acta neurologica Scandinavica

authors： Takashima H,Nakagawa M,Umehara F,Hirata K,Suehara M,Mayumi H,Yoshishige K,Matsuyama W,Saito M,Jonosono M,Arimura K,Osame M

更新日期：2003-01-01 00:00:00

abstract：UNLABELLED:FUNDAMENTALS AND OBJECTIVE: Multiple sclerosis (MS) is the prototype of demyelinating disease, but recently, it has been shown that the existence of axonal lesions contribute to irreversible central nervous system damage in this disease. Tau proteins are considered to be important for maintaining the stabili...

journal_title：Acta neurologica Scandinavica

authors： Jiménez-Jiménez FJ,Zurdo JM,Hernanz A,Medina-Acebrón S,de Bustos F,Barcenilla B,Sayed Y,Ayuso-Peralta L

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVES:To evaluate the long-term neuropsychological effects and magnetic resonance imaging (MRI) findings among retired patients with a history of exposure to carbon disulfide (CS2). MATERIAL AND METHODS:Seventy-four patients with a history of exposure to CS2 were divided into two equal groups according to their l...

journal_title：Acta neurologica Scandinavica

authors： Cho SK,Kim RH,Yim SH,Tak SW,Lee YK,Son MA

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVE:To describe clinical features of a patient with secretions of atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) during an epileptic attack. PATIENT:A 65-year-old woman experienced frequent bouts of polyuria, pyrexia and general fatigue after several years of a cerebral contusion involving ...

journal_title：Acta neurologica Scandinavica

authors： Obi T,Takatsu M,Konishi T,Mizoguchi K,Nishimura Y

更新日期：2002-10-01 00:00:00

abstract：OBJECTIVE:To study the relationship between cerebral hemodynamics and clinical performance in normal pressure hydrocephalus (NPH), before and after surgery. MATERIAL AND METHODS:Ten patients were studied prospectively before and 3 months after shunt surgery by means of transcranial Doppler (TCD). Clinical performance ...

journal_title：Acta neurologica Scandinavica

authors： Bakker SL,Boon AJ,Wijnhoud AD,Dippel DW,Delwel EJ,Koudstaal PJ

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVE:To clarify the relationship between mitochondrial DNA (mtDNA) sequence variations and phenotypes in patients with A3243G mutation. MATERIALS AND METHODS:We studied whole mtDNA sequences in two families with A3243G mutation and characteristic clinical features. Two brothers in Family 1 had shown thiamine defi...

journal_title：Acta neurologica Scandinavica

authors： Morovvati S,Nakagawa M,Sato Y,Hamada K,Higuchi I,Osame M

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVES:To determine whether anti-GM1 antibodies are increased in Parkinson's disease (PD). METHODS:Serum immunoglobulin M (IgM) and IgG anti-GM1 antibodies were detected by enzyme-linked immunosorbent assay (ELISA) in 147 patients with PD and in 186 age-matched normal control subjects. Sera were assayed at initial...

journal_title：Acta neurologica Scandinavica

authors： Zappia M,Crescibene L,Bosco D,Arabia G,Nicoletti G,Bagalà A,Bastone L,Napoli ID,Caracciolo M,Bonavita S,Di Costanzo A,Gambardella A,Quattrone A

更新日期：2002-07-01 00:00:00

abstract：OBJECTIVES:The GM2 gangliosidoses are a group of genetic disorders caused by the accumulation of ganglioside GM2 in neuronal cells. We examined the alpha- and beta-subunits of beta-hexosaminidases by a non-radioisotopes detecting system to evaluate whether it was a useful method for understanding of the pathophysiologi...

journal_title：Acta neurologica Scandinavica

authors： Utsumi K,Tsuji A,Kase R,Tanaka A,Tanaka T,Uyama E,Ozawa T,Sakuraba H,Komaba Y,Kawabe M,Iino Y,Katayama Y

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVES:Although there is growing evidence for a relation between Parkinson syndrome (PS) and mitochondriopathy (MCP), little is known about the frequency of PS in MCP. MATERIAL AND METHODS:This study assessed the frequency of PS in patients with MCP, the phenotype of these patients, and their response to anti-Park...

journal_title：Acta neurologica Scandinavica

authors： Finsterer J

更新日期：2002-05-01 00:00:00

abstract：OBJECTIVES:To describe the influence of the site of the bleeding on clinical spectrum and early outcome of patients with acute spontaneous intracerebral hemorrhage (ICH). MATERIALS AND METHODS:ICH was diagnosed in 229 (11%) of 2000 consecutive stroke patients included in a prospective stroke registry over a 10-year pe...

journal_title：Acta neurologica Scandinavica

authors： Arboix A,Comes E,García-Eroles L,Massons J,Oliveres M,Balcells M,Targa C

更新日期：2002-04-01 00:00:00

abstract：:Acute disseminated encephalomyelitis (ADEM) is an acute monophasic inflammatory and demyelinating disease of the central nervous system (CNS) occurring days to weeks after a virus infection or vaccination. Nephropathia epidemica (NE) is a haemorrhagic fever with renal syndrome caused by Puumala virus, with endemic reg...

journal_title：Acta neurologica Scandinavica

authors： Toivanen AL,Valanne L,Tatlisumak T

更新日期：2002-04-01 00:00:00

abstract：PURPOSE:To evaluate the relationship between people with epilepsy and birth order. METHODS:A case-control study of 336 epileptics, 15 years and above, and their 1961 full siblings. The data was analysed by birth order and then stratified by sibship size. The 95% confidence interval (CI) for each odds ratio (OR) was ob...

journal_title：Acta neurologica Scandinavica

authors： Obeid T,Awada A,Amene P,Oni G

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVES:To report a peculiar observation of a patient who developed a psychomotor inhibition state after a rapid cessation of lamotrigine (LTG). RESULTS:This man was referred to us at the age of 26 years for presurgical evaluation. His treatment [valproate (VPA), 1200 mg/day and LTG, 200 mg/day] was quickly decreas...

journal_title：Acta neurologica Scandinavica

authors： Gelisse P,Kissani N,Crespel A,Jafari H,Baldy-Moulinier M

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The role of the natural anticoagulants, antithrombin III (AT III), protein C (PC), and protein S (PS), in patients with mild to moderate ischemic stroke remains uncertain. We aimed to find out whether their levels in peripheral blood correlated with the severity of neurological deficit or can pre...

journal_title：Acta neurologica Scandinavica

authors： Haapaniemi E,Tatlisumak T,Soinne L,Syrjälä M,Kaste M

更新日期：2002-02-01 00:00:00

abstract：OBJECTIVES:To estimate the need for and the costs of carotid Doppler and carotid endarterectomy after stroke or TIA in non-selected hospitalized patients. MATERIAL AND METHODS:During 25 months hospitalized patients with stroke or TIA, in whom carotid endarterectomy could be relevant, were examined with carotid Doppler...

journal_title：Acta neurologica Scandinavica

authors： Jespersen HF,Jørgensen HS,Nakayama H,Reith J,Olsen TS

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVES:Myotonic dystrophy type 1 (DM1) is caused by large expansions of cytosine-thymine-guanine (CTG)-repeats in myotonic dystrophy protein kinase (DMPK)-gene. This gene is highly polymorphic in healthy individuals. It has been proposed that expanded alleles originated from the group of large sized normal alleles....

journal_title：Acta neurologica Scandinavica

authors： Culjković B,Stojković O,Vukosavić S,Savić D,Rakocevic V,Apostolski S,Romac S

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVES:To analyze the correlation between blood pressure (BP) variability and leukoaraiosis (LA) amount in patients with symptomatic cerebral small-vessel disease. MATERIALS AND METHODS:We included 25 hypertensive patients: 13 with Binswanger's disease (BD) and 12 with a first-ever lacunar infarction (LI). Baselin...

journal_title：Acta neurologica Scandinavica

authors： Martí-Fàbregas J,Valencia C,Pujol J,García-Sánchez C,Roca-Cusachs A,López-Contreras J,Solé MJ,Martí-Vilalta JL

更新日期：2001-12-01 00:00:00

abstract：OBJECTIVES:Fatigue is a disabling and dopa-resistant symptom in Parkinson's disease (PD). Pathological studies have shown that both peripheral and central cholinergic systems are involved in PD. Electrophysiological investigation showed decremental muscle responses following repetitive nerve stimulation (RNS). We hypot...

journal_title：Acta neurologica Scandinavica

authors： Hwang WJ,Lin TS

更新日期：2001-11-01 00:00:00

abstract：OBJECTIVES:We aimed to investigate associations between neuropsychological indices and normalized volumes of supratentorial structures, and the area of the corpus callosum. MATERIALS AND METHODS:We studied 40 patients with clinically definite MS, using 3D-acquired MRI (MPRAGE, Magnetization Prepared Rapid Acquisition ...

journal_title：Acta neurologica Scandinavica

authors： Edwards SG,Liu C,Blumhardt LD

更新日期：2001-10-01 00:00:00

abstract：OBJECTIVES:To report three cases of premature death in juvenile myoclonic epilepsy (JME), a benign form of idiopathic generalized epilepsy (IGE) in which no case of epilepsy-related death has been reported. MATERIAL AND METHODS:We retrospectively analyzed all medical records of JME patients first referred to two epile...

journal_title：Acta neurologica Scandinavica

authors： Genton P,Gelisse P

更新日期：2001-09-01 00:00:00

abstract：:We report a case of acute Wernicke encephalopathy (WE) in which apparent diffusion coefficient maps showed areas of increased diffusion in the bilateral medial thalami that corresponded to the hyperintense lesions on T2-weighted imaging. The hyperintense lesions on T2-weighted imaging disappeared with full recovery fr...

journal_title：Acta neurologica Scandinavica

authors： Oka M,Terae S,Kobayashi R,Kudoh K,Chu BC,Kaneko K,Yoshida M,Kaneda M,Suzuki Y,Miyasaka K

更新日期：2001-09-01 00:00:00

abstract：OBJECTIVES:When the vascular disorder of the cochleovestibular system is mentioned, the diagnosis is based on exclusion of other diseases. Since arteries of the cochleovestibular system cannot be directly visualized, physicians must deduce from the vascular risk factors and the vascular lesion of other territories to t...

journal_title：Acta neurologica Scandinavica

authors： Szirmai A,Küstel M,Pánczél G,Kocher I,Répássy G,Nagy Z

更新日期：2001-08-01 00:00:00

abstract：OBJECTIVE:Blepharoclonus (BLC) denotes a large amplitude, involuntary tremors of the orbicularis oculi muscles, observed during gentle closure of the eyelids. BLC may follow major head trauma. Four patients with Arnold-Chiari malformation (ACM) and BLC are described. MATERIALS AND METHODS:The first patient had facial ...

journal_title：Acta neurologica Scandinavica

authors： Jacome DE

更新日期：2001-08-01 00:00:00

abstract：OBJECTIVES:Little is known about the frequency of abnormal visually evoked potentials (VEPs) in patients with respiratory chain disorders (RCDs). We thus wanted to investigate the frequency of abnormal VEPs in RCDs, how often VEPs are abnormal despite normal visual acuity, and which of the VEP variables are most often ...

journal_title：Acta neurologica Scandinavica

authors： Finsterer J

更新日期：2001-07-01 00:00:00